Affecting Fluids and Electrolytes
Posted by Laura on December 8, 2009
Fluid and Electrolytes
Hormones regulating water retention and loss
ADH (anti-diuretic hormone) * regulates WATER excretion from the kidneys. As serum osmolality rises (>300), it stimulates osmoreceptors that stimulate thirst to ↑ H2O intake & stimulate ADH release to allow more water reabsorption in the kidney causing dilution of body fluids.
- water only, urine will be dark, scant, amber-colored,
- alcohol consumption turns ADH off and you are dehydrated the next day
- ADH & Aldosterone activate in ↓ BP
ADH keeps water from being loss through urination.
Aldosterone * Renin-Angiotensin System * regulates electrolyte balance from the kidneys by promoting Na+ & water retention and K+ loss
- with low blood volume such as internal bleeding or cut arm, kidneys kick in to reabsorb water
- this system works with salt to counteract effects of low blood volume & low BP to try to increase BP (water & salt reabsorbed)
Aldosterone, Renin-Angiotensin System keeps water and sodium from being loss through urination, though Potasium is loss.
ANP (atrial natriuretic peptide) * cardiac hormone found in atria & released when atria are stretched by increasing blood volume or BP (CHF) works to lower BP/volume through vasodilation & suppression of RAS (rennin-angiotensin system)
ANP is a marker found through testing, signifying CHF. ANP tries to lower BP/Volume that ADH and ARAS creates.
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